ID   1.14.14.195
DE   littorine mutase.
AN   CYP80F1.
CA   (R)-littorine + reduced [NADPH--hemoprotein reductase] + O2 = hyoscyamine
CA   aldehyde + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+).
CC   -!- Isolated from the plants Hyoscyamus niger (black henbane) and
CC       Anisodus acutangulus.
CC   -!- Involved in the biosynthesis of the alkaloids hyoscyamine (atropine)
CC       and scopalamine.
CC   -!- The reaction involves hydroxylation of littorine, giving a 1,2-diol
CC       that undergoes a spontaneous dehydration accompanied by pinacol
CC       rearrangement.
DR   A0A024CI64, C80F1_ATRBE;  Q1A1B0, C80F1_HYONI;
//