ID   1.14.14.197
DE   progesterone 11alpha-monooxygenase.
AN   CYP509C12.
AN   CYP68L1.
AN   CYP68L8.
AN   progesterone 11alpha-hydroxylase.
CA   progesterone + reduced [NADPH--hemoprotein reductase] + O2 = 11alpha-
CA   hydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + H2O +
CA   H(+).
CC   -!- A cytochrome P450 (heme-thiolate) enzyme.
CC   -!- The enzyme, isolated from fungi, can hydroxylate testosterone,
CC       androst-4-ene-3,17-dione, and 11-deoxycorticosterone, forming the
CC       respective 11alpha-hydroxy compounds (cf. EC 1.14.15.4).
CC   -!- The CYP509C12 enzyme from Rhizopus arrhizus can also 6-hydroxylate
CC       testosterone and 11-deoxycorticosterone, forming the respective beta-
CC       hydroxy compounds.
CC   -!- Formerly EC 1.14.99.14.
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