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ENZYME

ENZYME entry: EC 1.14.14.20

PURL: https://purl.expasy.org/enzyme/EC/1.14.14.20
Accepted Name
phenol 2-monooxygenase (FADH2)
Reaction catalysed
phenol + FADH2 + O2 = catechol + FAD + H2O + H(+)
Comment(s)
  • The enzyme catalyzes the ortho-hydroxylation of simple phenols into the corresponding catechols.
  • It accepts 4-methylphenol, 4-chlorophenol, and 4-fluorophenol as well as 4-nitrophenol, 3-nitrophenol, and resorcinol.
  • The enzyme is part of a two-component system that also includes an NADH-dependent flavin reductase. cf. EC 1.14.13.7.
  • It is strictly dependent on FADH2 and does not accept FMNH2.
Cross-references
BRENDA1.14.14.20
EC2PDB1.14.14.20
ExplorEnz1.14.14.20
KEGG Ligand Database for Enzyme Nomenclature1.14.14.20
IUBMB Enzyme Nomenclature1.14.14.20
MEDLINEFind literature relating to 1.14.14.20
MetaCyc1.14.14.20
Rhea expert-curated reactions1.14.14.20

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-