ENZYME entry: EC 1.14.14.20
| Accepted Name |
|---|
| Phenol 2-monooxygenase (FADH(2)).
|
| Reaction catalysed |
|---|
| Phenol + FADH(2) + O(2) <=> catechol + FAD + H(2)O |
| Comment(s) |
|---|
- The enzyme catalyzes the ortho-hydroxylation of simple phenols into
the corresponding catechols.
- It accepts 4-methylphenol, 4-chlorophenol, and 4-fluorophenol as well
as 4-nitrophenol, 3-nitrophenol, and resorcinol.
- The enzyme is part of a two-component system that also includes an
NADH-dependent flavin reductase.
- It is strictly dependent on FADH(2) and does not accept FMNH(2).
- Cf. EC 1.14.13.7.
|
| Cross-references |
|---|
| BRENDA | 1.14.14.20 |
| EC2PDB | 1.14.14.20 |
| ExplorEnz | 1.14.14.20 |
| PRIAM enzyme-specific profiles | 1.14.14.20 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.14.20 |
| IUBMB Enzyme Nomenclature | 1.14.14.20 |
| IntEnz | 1.14.14.20 |
| MEDLINE | Find literature relating to 1.14.14.20 |
| MetaCyc | 1.14.14.20 |
| Rhea expert-curated reactions | 1.14.14.20 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.14.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-