ENZYME entry: EC 1.14.14.20
Accepted Name |
Phenol 2-monooxygenase (FADH(2)).
|
Reaction catalysed |
Phenol + FADH(2) + O(2) <=> catechol + FAD + H(2)O |
Comment(s) |
- The enzyme catalyzes the ortho-hydroxylation of simple phenols into
the corresponding catechols.
- It accepts 4-methylphenol, 4-chlorophenol, and 4-fluorophenol as well
as 4-nitrophenol, 3-nitrophenol, and resorcinol.
- The enzyme is part of a two-component system that also includes an
NADH-dependent flavin reductase.
- It is strictly dependent on FADH(2) and does not accept FMNH(2).
- Cf. EC 1.14.13.7.
|
Cross-references |
BRENDA | 1.14.14.20 |
EC2PDB | 1.14.14.20 |
ExplorEnz | 1.14.14.20 |
PRIAM enzyme-specific profiles | 1.14.14.20 |
KEGG Ligand Database for Enzyme Nomenclature | 1.14.14.20 |
IUBMB Enzyme Nomenclature | 1.14.14.20 |
IntEnz | 1.14.14.20 |
MEDLINE | Find literature relating to 1.14.14.20 |
MetaCyc | 1.14.14.20 |
Rhea expert-curated reactions | 1.14.14.20 |
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.14.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-