ID 1.14.14.23 DE cholesterol 7alpha-monooxygenase. AN cholesterol 7alpha-hydroxylase. AN CYP7A1. CA cholesterol + O2 + reduced [NADPH--hemoprotein reductase] = 7alpha- CA hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein CA reductase]. CC -!- Catalyzes the first step in the biosynthesis of bile acids. CC -!- The direct electron donor to the enzyme is EC 1.6.2.4. CC -!- Formerly EC 1.14.13.17. DR P46634, CP7A1_CRIGR; P22680, CP7A1_HUMAN; Q64505, CP7A1_MOUSE; DR O46491, CP7A1_PIG ; P51542, CP7A1_RABIT; P18125, CP7A1_RAT ; //