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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
Isobutylamine N-monooxygenase.
Reaction catalysed
  • 2-methylpropan-1-amine + FADH(2) + O(2) <=> N-(2-methylpropyl)hydroxylamine + FAD + H(2)O
  • 2-methylpropan-1-amine + FMNH(2) + O(2) <=> N-(2-methylpropyl)hydroxylamine + FMN + H(2)O
  • The enzyme, characterized from the bacterium Streptomyces viridifaciens, is part of a two component system that also includes a flavin reductase, which provides reduced flavin mononucleotide for this enzyme.
  • The enzyme, which is involved in the biosynthesis of the azoxy antibiotic valanimycin, has a similar activity with either FMNH(2) or FADH(2).
  • It exhibits broad specificity, and also accepts propan-1-amine, butan-1-amine, butan-2-amine and benzylamine.
PRIAM enzyme-specific profiles1.14.14.30
KEGG Ligand Database for Enzyme Nomenclature1.14.14.30
IUBMB Enzyme Nomenclature1.14.14.30
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