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ENZYME entry: EC 1.14.14.36

Accepted Name
Tyrosine N-monooxygenase.
Alternative Name(s)
CYP79A1.
Tyrosine N-hydroxylase.
Reaction catalysed
L-tyrosine + 2 O(2) + 2 [reduced NADPH--hemoprotein reductase] <=> (E)-(4-hydroxyphenylacetaldehyde oxime) + 2 [oxidized NADPH--hemoprotein reductase] + CO(2) + 3 H(2)O
Cofactor(s)
Heme-thiolate.
Comment(s)
  • The enzyme from Sorghum is involved in the biosynthesis of the cyanogenic glucoside dhurrin.
  • In Sinapis alba (white mustard) the enzyme is involved in the biosynthesis of the glucosinolate sinalbin.
  • Formerly EC 1.14.13.41.
Cross-references
PROSITEPDOC00081
BRENDA1.14.14.36
EC2PDB1.14.14.36
ExplorEnz1.14.14.36
PRIAM enzyme-specific profiles1.14.14.36
KEGG Ligand Database for Enzyme Nomenclature1.14.14.36
IUBMB Enzyme Nomenclature1.14.14.36
IntEnz1.14.14.36
MEDLINEFind literature relating to 1.14.14.36
MetaCyc1.14.14.36
UniProtKB/Swiss-Prot
Q43135, C79A1_SORBI

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