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ENZYME

ENZYME entry: EC 1.14.14.37

Accepted Name
4-hydroxyphenylacetaldehyde oxime monooxygenase
Alternative Name(s)
4-hydroxybenzeneacetaldehyde oxime monooxygenase
CYP71E1
cytochrome P450II-dependent monooxygenase
Reaction catalysed
(E)-4-hydroxyphenylacetaldehyde oxime + O2 + reduced [NADPH--hemoprotein reductase] = (S)-4-hydroxymandelonitrile + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]
Comment(s)
  • Involved in the biosynthesis of the cyanogenic glucoside dhurrin in sorghum.
  • It catalyzes three different activities - isomerization of the (E) isomer to the (Z) isomer, dehydration, and C-hydroxylation.
  • Formerly EC 1.14.13.68.
Cross-references
BRENDA1.14.14.37
EC2PDB1.14.14.37
ExplorEnz1.14.14.37
PRIAM enzyme-specific profiles1.14.14.37
KEGG Ligand Database for Enzyme Nomenclature1.14.14.37
IUBMB Enzyme Nomenclature1.14.14.37
IntEnz1.14.14.37
MEDLINEFind literature relating to 1.14.14.37
MetaCyc1.14.14.37
Rhea expert-curated reactions1.14.14.37
UniProtKB/Swiss-Prot
O48958, C71E1_SORBI

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