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ENZYME entry: EC 22.214.171.124
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|L-phenylalanine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> (E)-phenylacetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]|
- This enzyme, found in plants, catalyzes two successive
N-hydroxylations of L-phenylalanine, a committed step in the
biosynthesis of benzylglucosinolate and the cyanogenic glucosides
(R)-prunasin and (R)-amygdalin.
- The product of the two hydroxylations, N,N-dihydroxy-L-phenylalanine,
is labile and undergoes dehydration followed by decarboxylation,
producing an oxime.
- It is still not known whether the decarboxylation is spontaneous or
catalyzed by the enzyme.
- Formerly EC 126.96.36.199 and EC 1.14.13.n1.
|PRIAM enzyme-specific profiles||188.8.131.52|
|KEGG Ligand Database for Enzyme Nomenclature||184.108.40.206|
|IUBMB Enzyme Nomenclature||220.127.116.11|
|MEDLINE||Find literature relating to 18.104.22.168|
|Rhea expert-curated reactions||22.214.171.124|
entries corresponding to 1.14.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-