ID   1.14.14.46
DE   pimeloyl-[acyl-carrier protein] synthase.
AN   CYP107H1.
CA   a C2-C8-saturated long-chain fatty acyl-[ACP] + 2 reduced [flavodoxin] +
CA   3 O2 = 6-carboxyhexanoyl-[ACP] + a fatty aldehyde + 2 oxidized
CA   [flavodoxin] + 3 H2O + 3 H(+).
CC   -!- Catalyzes an oxidative C-C bond cleavage of long-chain acyl-[acyl-
CC       carrier protein]s of various lengths to generate pimeloyl-[acyl-
CC       carrier protein], an intermediate in the biosynthesis of biotin.
CC   -!- The preferred substrate of the enzyme from the bacterium Bacillus
CC       subtilis is palmitoyl-[acyl-carrier protein] which then gives
CC       heptanal as the alkanal.
CC   -!- The mechanism is similar to EC 1.14.15.6, followed by a hydroxylation
CC       step, which may occur spontaneously.
CC   -!- Formerly EC 1.14.15.12.
DR   P53554, BIOI_BACSU ;
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