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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.14.14.5

Accepted Name
Alkanesulfonate monooxygenase.
Alternative Name(s)
FMNH(2)-dependent aliphatic sulfonate monooxygenase.
Sulfate starvation-induced protein 6.
Reaction catalysed
An alkanesulfonate (R-CH(2)-SO(3)H) + FMNH(2) + O(2) <=> an aldehyde (R-CHO) + FMN + sulfite + H(2)O
Comment(s)
  • The enzyme from Escherichia coli catalyzes the desulfonation of a wide range of aliphatic sulfonates (unsubstituted C(1)- to C(14)- sulfonates as well as substituted C(2)-sulfonates).
  • Does not desulfonate taurine (2-aminoethanesulfonate) or aromatic sulfonates.
  • Does not use FMN as a bound cofactor.
  • Instead, it uses reduced FMN (i.e., FMNH(2)) as a substrate.
  • FMNH(2) is provided by SsuE, the associated FMN reductase (EC 1.5.1.38).
Cross-references
BRENDA1.14.14.5
EC2PDB1.14.14.5
ExplorEnz1.14.14.5
PRIAM enzyme-specific profiles1.14.14.5
KEGG Ligand Database for Enzyme Nomenclature1.14.14.5
IUBMB Enzyme Nomenclature1.14.14.5
IntEnz1.14.14.5
MEDLINEFind literature relating to 1.14.14.5
MetaCyc1.14.14.5
UniProtKB/Swiss-Prot
Q9I1C2, MSUD_PSEAE;  Q98CB9, SSUD1_RHILO;  Q98DT4, SSUD2_RHILO;  
A1TRM3, SSUD_ACIAC;  Q8UAE8, SSUD_AGRFC;  C1DN48, SSUD_AZOVD;  
Q65M61, SSUD_BACLD;  P40402, SSUD_BACSU;  A7Z2Q3, SSUD_BACVZ;  
Q89ER2, SSUD_BRADU;  Q3JSR8, SSUD_BURP1;  Q2SVM8, SSUD_BURTA;  
Q9KHR3, SSUD_BUTSP;  A8AID7, SSUD_CITK8;  A7MEW3, SSUD_CROS8;  
Q1LNM2, SSUD_CUPMC;  Q0K9I0, SSUD_CUPNH;  Q46ZU3, SSUD_CUPNJ;  
B3R2K7, SSUD_CUPTR;  A9C3F6, SSUD_DELAS;  A7ZK27, SSUD_ECO24;  
B7UN21, SSUD_ECO27;  B7MHP4, SSUD_ECO45;  B7LE35, SSUD_ECO55;  
Q8XDD9, SSUD_ECO57;  B5YT69, SSUD_ECO5E;  B7NM39, SSUD_ECO7I;  
B7MS53, SSUD_ECO81;  B7M864, SSUD_ECO8A;  C4ZQ61, SSUD_ECOBW;  
B1X8N9, SSUD_ECODH;  A7ZYN8, SSUD_ECOHS;  A1A9L2, SSUD_ECOK1;  
Q0TJB9, SSUD_ECOL5;  Q8FJ93, SSUD_ECOL6;  B1IVZ6, SSUD_ECOLC;  
P80645, SSUD_ECOLI;  B7N3A4, SSUD_ECOLU;  B6I909, SSUD_ECOSE;  
B1LJS7, SSUD_ECOSM;  Q1RDS2, SSUD_ECOUT;  A4W8V4, SSUD_ENT38;  
D2TDP0, SSUD_ERWP6;  B2VC88, SSUD_ERWT9;  B7LNV2, SSUD_ESCF3;  
B7KX11, SSUD_METC4;  B2JKA8, SSUD_PARP8;  B2T3J1, SSUD_PARPJ;  
Q6CYU4, SSUD_PECAS;  C6DGK1, SSUD_PECCP;  A1VPZ7, SSUD_POLNA;  
Q48H03, SSUD_PSE14;  Q9HYG2, SSUD_PSEAE;  Q1IGL6, SSUD_PSEE4;  
A4Y0F3, SSUD_PSEMY;  A5VX17, SSUD_PSEP1;  B0KH56, SSUD_PSEPG;  
Q88R95, SSUD_PSEPK;  O85764, SSUD_PSEPU;  B1JEV9, SSUD_PSEPW;  
Q87ZG3, SSUD_PSESM;  Q9KHS2, SSUD_PSESP;  Q4ZRE3, SSUD_PSEU2;  
B2UAU3, SSUD_RALPJ;  Q8XZQ6, SSUD_RALSO;  B3Q1C3, SSUD_RHIE6;  
Q6N6K3, SSUD_RHOPA;  B3QIN8, SSUD_RHOPT;  A8GCK1, SSUD_SERP5;  
Q0T6A4, SSUD_SHIF8;  P59189, SSUD_SHIFL;  A9FK50, SSUD_SORC5;  
C5CNW9, SSUD_VARPS;  Q8PP38, SSUD_XANAC;  A7FDL9, SSUD_YERP3;  
Q1C1S2, SSUD_YERPA;  B2K4U5, SSUD_YERPB;  Q8ZB04, SSUD_YERPE;  
Q1CDQ8, SSUD_YERPN;  A4TH89, SSUD_YERPP;  Q665B4, SSUD_YERPS;  
B1JKC0, SSUD_YERPY;  

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