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ENZYME entry: EC 1.14.14.51

Accepted Name
(S)-limonene 6-monooxygenase.
Alternative Name(s)
(-)-limonene 6-hydroxylase.
(-)-limonene 6-monooxygenase.
Reaction catalysed
(S)-limonene + [reduced NADPH--hemoprotein reductase] + O(2) <=> (-)-trans-carveol + [oxidized NADPH--hemoprotein reductase] + H(2)O
Cofactor(s)
Heme-thiolate.
Comment(s)
  • The enzyme participates in the biosynthesis of (-)-carvone, which is responsible for the aroma of spearmint.
  • Formerly EC 1.14.13.48.
Cross-references
PROSITEPDOC00081
BRENDA1.14.14.51
EC2PDB1.14.14.51
ExplorEnz1.14.14.51
PRIAM enzyme-specific profiles1.14.14.51
KEGG Ligand Database for Enzyme Nomenclature1.14.14.51
IUBMB Enzyme Nomenclature1.14.14.51
IntEnz1.14.14.51
MEDLINEFind literature relating to 1.14.14.51
MetaCyc1.14.14.51
Rhea expert-curated reactions1.14.14.51
UniProtKB/Swiss-Prot
Q6WKZ1, C71DI_MENGR;  Q9XHE8, C71DI_MENSP;  P0DO35, CP178_ORIVU;  
P0DO40, CP180_ORIMA;  P0DO39, CP180_ORIVU;  P0DO38, CP180_THYVU;  
P0DO41, CP181_ORIVU;  P0DO42, CP181_THYVU;  P11712, CP2C9_HUMAN;  
P33261, CP2CJ_HUMAN;  O85057, LIHY_GEOSE;  

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