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ENZYME

ENZYME entry: EC 1.14.14.52

Accepted Name
(S)-limonene 7-monooxygenase
Alternative Name(s)
(-)-limonene 7-monooxygenase
(-)-limonene hydroxylase
(-)-limonene monooxygenase
Reaction catalysed
(4S)-limonene + O2 + reduced [NADPH--hemoprotein reductase] = (4S)-perillyl alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
Comment(s)
  • The enzyme, characterized from the plant Perilla frutescens, participates in the biosynthesis of perillyl aldehyde, the major constituent of the essential oil that accumulates in the glandular trichomes of this plant.
  • Some forms of the enzyme also catalyze the oxidation of (-)-perillyl alcohol to (-)-perillyl aldehyde.
  • Formerly EC 1.14.13.49.
Cross-references
BRENDA1.14.14.52
EC2PDB1.14.14.52
ExplorEnz1.14.14.52
PRIAM enzyme-specific profiles1.14.14.52
KEGG Ligand Database for Enzyme Nomenclature1.14.14.52
IUBMB Enzyme Nomenclature1.14.14.52
IntEnz1.14.14.52
MEDLINEFind literature relating to 1.14.14.52
MetaCyc1.14.14.52
Rhea expert-curated reactions1.14.14.52
UniProtKB/Swiss-Prot
P11712, CP2C9_HUMANP33261, CP2CJ_HUMANO85057, LIHY_GEOSE

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