ENZYME entry: EC 1.14.14.55
| Accepted Name |
|---|
| Quinine 3-monooxygenase.
|
| Alternative Name(s) |
|---|
| CYP3A4. |
| Nifedipine oxidase. |
| Quinine 3-hydroxylase. |
| Reaction catalysed |
|---|
| Quinine + [reduced NADPH--hemoprotein reductase] + O(2) <=> 3-hydroxyquinine + [oxidized NADPH--hemoprotein reductase] + H(2)O |
| Cofactor(s) |
|---|
| Heme-thiolate.
|
| Comment(s) |
|---|
| Formerly EC 1.14.13.67.
|
| Cross-references |
|---|
| PROSITE | PDOC00081 |
| BRENDA | 1.14.14.55 |
| EC2PDB | 1.14.14.55 |
| ExplorEnz | 1.14.14.55 |
| PRIAM enzyme-specific profiles | 1.14.14.55 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.14.55 |
| IUBMB Enzyme Nomenclature | 1.14.14.55 |
| IntEnz | 1.14.14.55 |
| MEDLINE | Find literature relating to 1.14.14.55 |
| MetaCyc | 1.14.14.55 |
| UniProtKB/Swiss-Prot |
|
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