ID 1.14.14.56 DE 1,8-cineole 2-exo-monooxygenase. AN CYP3A4. CA 1,8-cineole + reduced [NADPH--hemoprotein reductase] + O2 = 2-exo- CA hydroxy-1,8-cineole + oxidized [NADPH--hemoprotein reductase] + H2O + CA H(+). CC -!- The mammalian enzyme, expressed in liver microsomes, performs a CC variety of oxidation reactions of structurally unrelated compounds, CC including stereoids, fatty acids, and xenobiotics. cf. EC 1.14.14.55, CC EC 1.14.14.57 and EC 1.14.14.73. CC -!- Formerly EC 1.14.13.157. DR P08684, CP3A4_HUMAN; //