ENZYME entry: EC 1.14.14.58

PURL: https://purl.expasy.org/enzyme/EC/1.14.14.58

Accepted Name

trimethyltridecatetraene synthase

Alternative Name(s)

CYP82G1

CYP92C5

CYP92C6

DMNT/TMTT homoterpene synthase

Reaction catalysed

(6E,10E)-geranyllinalool + reduced [NADPH--hemoprotein reductase] + O2 = (3E,7E)-4,8,12-trimethyltrideca 1,3,7,11-tetraene + but-3-en-2-one + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Comment(s)

Isolated from the plants Arabidopsis thaliana (thale cress) and Zea mays (maize).
It forms this C16 homoterpene in response to herbivore attack.
In vitro some variants of the enzyme also convert (3S,6E)-nerolidol to (3E)-4,8-dimethylnona-1,3,7-triene (see EC 1.14.14.59).

Cross-references

BRENDA

1.14.14.58

EC2PDB

1.14.14.58

ExplorEnz

1.14.14.58

KEGG Ligand Database for Enzyme Nomenclature

1.14.14.58

IUBMB Enzyme Nomenclature

1.14.14.58

MEDLINE

Find literature relating to 1.14.14.58

MetaCyc

1.14.14.58

Rhea expert-curated reactions

1.14.14.58

UniProtKB/Swiss-Prot

Q9LSF8, C82G1_ARATH

A0A1D6HSP4, C92C5_MAIZE

A0A1D6F9Y9, C92C6_MAIZE

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