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ENZYME entry: EC 1.14.14.60

Accepted Name
Ferruginol monooxygenase.
Alternative Name(s)
CYP76AH24.
CYP76AH3.
Reaction catalysed
Ferruginol + [reduced NADPH--hemoprotein reductase] + O(2) <=> 11-hydroxyferruginol + [oxidized NADPH--hemoprotein reductase] + H(2)O
Comment(s)
  • Isolated from the plants Salvia pomifera (apple sage) and Salvia miltiorrhiza (danshen).
  • 11-hydroxyferruginol is a precursor of carnosic acid, a potent antioxidant.
Cross-references
BRENDA1.14.14.60
EC2PDB1.14.14.60
ExplorEnz1.14.14.60
PRIAM enzyme-specific profiles1.14.14.60
KEGG Ligand Database for Enzyme Nomenclature1.14.14.60
IUBMB Enzyme Nomenclature1.14.14.60
IntEnz1.14.14.60
MEDLINEFind literature relating to 1.14.14.60
MetaCyc1.14.14.60
Rhea expert-curated reactions1.14.14.60
UniProtKB/Swiss-Prot
A0A0C5Q4Y6, C76H2_ROSOF;  A0A0C5QRZ2, C76H2_SALFT;  A0A0S1TP26, C76H2_SALPM;  
A0A0Y0GRS3, C76H3_SALMI;  

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