ID   1.14.14.74
DE   albendazole monooxygenase (hydroxylating).
AN   CYP2J2.
CA   albendazole + reduced [NADPH--hemoprotein reductase] + O2 =
CA   hydroxyalbendazole + oxidized [NADPH--hemoprotein reductase] + H2O +
CA   H(+).
CC   -!- CYP2J2 is a microsomal cytochrome P450 monooxygenase that catalyzes
CC       the hydroxylation of the terminal carbon of the propylsulfanyl chain
CC       in albendazole, a broad-spectrum anthelmintic used against
CC       gastrointestinal nematodes and the larval stages of cestodes. cf.
CC       EC 1.14.14.73.
DR   P51589, CP2J2_HUMAN;
//