ID 1.14.14.78 DE phylloquinone omega-hydroxylase. AN CYP4F11. AN CYP4F2. CA O2 + phylloquinone + reduced [NADPH--hemoprotein reductase] = H(+) + CA H2O + omega-hydroxyphylloquinone + oxidized [NADPH--hemoprotein CA reductase]. CC -!- A cytochrome P450 (heme-thiolate) protein isolated from human tissue. CC -!- The enzyme will also act on menaquinone-4. CC -!- Prolonged action of CYP4F2, but not CYP4F11, on the omega hydroxyl CC group oxidizes it to the corresponding carboxylic acid. CC -!- CYP4F2 also oxidizes leukotriene B4; see EC 1.14.13.30. CC -!- Formerly EC 1.14.13.194. DR P78329, CP4F2_HUMAN; Q9HBI6, CP4FB_HUMAN; //