ID   1.14.14.79
DE   docosahexaenoic acid omega-hydroxylase.
AN   CYP4F3B.
AN   CYP4V2.
CA   (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein
CA   reductase] + O2 = 22-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate +
CA   oxidized [NADPH--hemoprotein reductase] + H2O + H(+).
CC   -!- A cytochrome P450 (heme-thiolate) protein isolated from human eye
CC       tissue.
CC   -!- Defects in the enzyme are associated with Bietti crystalline
CC       corneoretinal dystrophy.
CC   -!- The enzyme also produces some 21-hydroxydocosahexaenoate.
CC   -!- Acts in a similar way on icosapentaenoic acid.
CC   -!- Formerly EC 1.14.13.199.
DR   P78329, CP4F2_HUMAN;  Q08477, CP4F3_HUMAN;  Q9HBI6, CP4FB_HUMAN;
DR   Q6ZWL3, CP4V2_HUMAN;  Q9DBW0, CP4V2_MOUSE;  Q5RCN6, CP4V2_PONAB;
DR   A2RRT9, CP4V2_RAT  ;
//