ID   1.14.14.80
DE   long-chain fatty acid omega-monooxygenase.
AN   CYP4A.
AN   CYP52M1.
AN   CYP704B1.
AN   CYP86A.
CA   an omega-methyl-long-chain fatty acid + O2 + reduced [NADPH--hemoprotein
CA   reductase] = an omega-hydroxy-long-chain fatty acid + H(+) + H2O +
CA   oxidized [NADPH--hemoprotein reductase].
CC   -!- A cytochrome P450 (heme thiolate) enzyme.
CC   -!- The plant enzyme CYP704B1, which is involved in the synthesis of
CC       sporopollenin, a complex polymer found at the outer layer of spores
CC       and pollen, acts on palmitate (18:0), stearate (18:0) and oleate
CC       (18:1).
CC   -!- The plant enzyme CYP86A1 also acts on laurate (12:0).
CC   -!- The enzyme from the yeast Starmerella bombicola (CYP52M1) acts on C16
CC       to C20 saturated and unsaturated fatty acids and can also hydroxylate
CC       the (omega-1) position.
CC   -!- The mammalian enzyme CYP4A acts on laurate (12:0), myristate (14:0),
CC       palmitate (16:0), oleate (18:1), and arachidonate (20:4).
CC   -!- Formerly EC 1.14.13.205.
DR   Q9C788, C70B1_ARATH;  P48422, C86A1_ARATH;  Q0IIF9, CP2U1_BOVIN;
DR   Q7Z449, CP2U1_HUMAN;  Q9CX98, CP2U1_MOUSE;  Q4V8D1, CP2U1_RAT  ;
DR   P20816, CP4A2_RAT  ;  P14579, CP4A5_RABIT;  P14580, CP4A6_RABIT;
DR   P14581, CP4A7_RABIT;  O88833, CP4AA_MOUSE;  P08516, CP4AA_RAT  ;
DR   Q02928, CP4AB_HUMAN;  P20817, CP4AE_RAT  ;  Q5TCH4, CP4AM_HUMAN;
DR   Q8SPK1, CP4AO_PIG  ;  Q8SPK0, CP4AP_PIG  ;  Q9HBI6, CP4FB_HUMAN;
DR   Q6ZWL3, CP4V2_HUMAN;  Q9DBW0, CP4V2_MOUSE;  Q5RCN6, CP4V2_PONAB;
DR   A2RRT9, CP4V2_RAT  ;  B8QHP3, CP52E_STABO;  B8QHP1, CP52M_STABO;
DR   B8QHP5, CP52N_STABO;
//