ID   1.14.14.81
DE   flavonoid 3',5'-hydroxylase.
AN   F3',5'H.
AN   F3'5'H.
CA   a 3',5'-unsubstituted flavanone + 2 O2 + 2 reduced [NADPH--hemoprotein
CA   reductase] = a 3',5'-dihydroxyflavanone + 2 H(+) + 2 H2O + 2 oxidized
CA   [NADPH--hemoprotein reductase].
CC   -!- A cytochrome P450 (heme-thiolate) protein found in plants.
CC   -!- The 3',5'-dihydroxyflavanone is formed via the 3'-hydroxyflavanone.
CC   -!- In Petunia hybrida the enzyme acts on naringenin, eriodictyol,
CC       dihydroquercetin (taxifolin) and dihydrokaempferol (aromadendrin).
CC   -!- The enzyme catalyzes the hydroxylation of 5,7,4'-trihydroxyflavanone
CC       (naringenin) at either the 3' position to form eriodictyol or at both
CC       the 3' and 5' positions to form 5,7,3',4',5'-pentahydroxyflavanone
CC       (dihydrotricetin).
CC   -!- The enzyme also catalyzes the hydroxylation of
CC       3,5,7,3',4'-pentahydroxyflavanone (taxifolin) at the 5' position,
CC       forming ampelopsin.
CC   -!- Formerly EC 1.14.13.88.
DR   P48418, C75A1_PETHY;  P37120, C75A2_SOLME;  P48419, C75A3_PETHY;
DR   Q96581, C75A4_GENTR;  Q96418, C75A5_EUSER;  O04773, C75A6_CAMME;
DR   O04790, C75A7_EUSER;  A0A4D6Q414, CYP2_CROXC ;
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