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ENZYME entry: EC 1.14.14.83

Accepted Name
geraniol 8-hydroxylase.
Alternative Name(s)
CYP76B10.
CYP76B6.
G10H.
Reaction catalysed
(2E)-geraniol + O2 + reduced [NADPH--hemoprotein reductase] <=> (6E)-8-hydroxygeraniol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
Comment(s)
  • A cytochrome P450 (heme thiolate) protein found in plants.
  • Also hydroxylates nerol and citronellol, cf. EC 1.14.14.84.
  • The recommended numbering of geraniol gives 8-hydroxygeraniol as the product rather than 10-hydroxygeraniol.
  • The cloned enzyme also catalyzed, but less efficiently, the 3'-hydroxylation of naringenin (cf. EC 1.14.14.82).
  • Formerly EC 1.14.13.152.
Cross-references
BRENDA1.14.14.83
EC2PDB1.14.14.83
ExplorEnz1.14.14.83
PRIAM enzyme-specific profiles1.14.14.83
KEGG Ligand Database for Enzyme Nomenclature1.14.14.83
IUBMB Enzyme Nomenclature1.14.14.83
IntEnz1.14.14.83
MEDLINEFind literature relating to 1.14.14.83
MetaCyc1.14.14.83
Rhea expert-curated reactions1.14.14.83
UniProtKB/Swiss-Prot
Q8VWZ7, C76B6_CATRO;  D1MI46, C76BA_SWEMU;  

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