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ENZYME entry: EC 1.14.14.86

Accepted Name
Ent-kaurene monooxygenase.
Alternative Name(s)
Ent-kaurene oxidase.
Reaction catalysed
Ent-kaur-16-ene + 3 [reduced NADPH--hemoprotein reductase] + 3 O(2) <=> ent-kaur-16-en-19-oate + 3 [oxidized NADPH--hemoprotein reductase] + 4 H(2)O
Comment(s)
  • A cytochrome P450 (heme thiolate) protein found in plants.
  • Catalyzes three successive oxidations of the 4-methyl group of ent- kaurene giving kaurenoic acid.
  • Formerly EC 1.14.13.78.
Cross-references
PROSITEPDOC00081
BRENDA1.14.14.86
EC2PDB1.14.14.86
ExplorEnz1.14.14.86
PRIAM enzyme-specific profiles1.14.14.86
KEGG Ligand Database for Enzyme Nomenclature1.14.14.86
IUBMB Enzyme Nomenclature1.14.14.86
IntEnz1.14.14.86
MEDLINEFind literature relating to 1.14.14.86
MetaCyc1.14.14.86
Rhea expert-curated reactions1.14.14.86
UniProtKB/Swiss-Prot
Q5Z5R4, C7016_ORYSJ;  S0E3D0, GA2_GIBF5;  Q93ZB2, KO1_ARATH;  
O94142, KO1_GIBFU;  Q701P2, KO1_GIBIN;  A0A0G2RKY1, KO_SALMI;  

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