ENZYME entry: EC 1.14.14.87
Accepted Name |
2-hydroxyisoflavanone synthase.
|
Alternative Name(s) |
CYT93C. |
Isoflavonoid synthase. |
Reaction catalysed |
- Liquiritigenin + O(2) + [reduced NADPH--hemoprotein reductase] <=> 2,4',7-trihydroxyisoflavanone + H(2)O + [oxidized NADPH--hemoprotein reductase]
- (2S)-naringenin + O(2) + [reduced NADPH--hemoprotein reductase] <=> 2,4',5,7-tetrahydroxyisoflavanone + H(2)O + [oxidized NADPH--hemoprotein reductase]
|
Comment(s) |
- A cytochrome P450 (heme thiolate) protein found in plants.
- The reaction involves the migration of the 2-phenyl group of the
flavanone to the 3-position of the isoflavanone.
- The 2-hydroxyl group is derived from the oxygen molecule.
- EC 4.2.1.105 acts on the products with loss of water and formation of
genistein and daidzein, respectively.
- Formerly EC 1.14.13.86 and EC 1.14.13.136.
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Cross-references |
BRENDA | 1.14.14.87 |
EC2PDB | 1.14.14.87 |
ExplorEnz | 1.14.14.87 |
PRIAM enzyme-specific profiles | 1.14.14.87 |
KEGG Ligand Database for Enzyme Nomenclature | 1.14.14.87 |
IUBMB Enzyme Nomenclature | 1.14.14.87 |
IntEnz | 1.14.14.87 |
MEDLINE | Find literature relating to 1.14.14.87 |
MetaCyc | 1.14.14.87 |
Rhea expert-curated reactions | 1.14.14.87 |
UniProtKB/Swiss-Prot |
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