A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.14.14.87
| Accepted Name |
|---|
| 2-hydroxyisoflavanone synthase.
|
| Alternative Name(s) |
|---|
| CYT93C. |
| Isoflavonoid synthase. |
| Reaction catalysed |
|---|
- Liquiritigenin + O(2) + [reduced NADPH--hemoprotein reductase] <=> 2,4',7-trihydroxyisoflavanone + H(2)O + [oxidized NADPH--hemoprotein reductase]
- (2S)-naringenin + O(2) + [reduced NADPH--hemoprotein reductase] <=> 2,4',5,7-tetrahydroxyisoflavanone + H(2)O + [oxidized NADPH--hemoprotein reductase]
|
| Comment(s) |
|---|
- A cytochrome P450 (heme thiolate) protein found in plants.
- The reaction involves the migration of the 2-phenyl group of the
flavanone to the 3-position of the isoflavanone.
- The 2-hydroxyl group is derived from the oxygen molecule.
- EC 4.2.1.105 acts on the products with loss of water and formation of
genistein and daidzein, respectively.
- Formerly EC 1.14.13.86 and EC 1.14.13.136.
|
| Cross-references |
|---|
| BRENDA | 1.14.14.87 |
| EC2PDB | 1.14.14.87 |
| ExplorEnz | 1.14.14.87 |
| PRIAM enzyme-specific profiles | 1.14.14.87 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.14.87 |
| IUBMB Enzyme Nomenclature | 1.14.14.87 |
| IntEnz | 1.14.14.87 |
| MEDLINE | Find literature relating to 1.14.14.87 |
| MetaCyc | 1.14.14.87 |
| UniProtKB/Swiss-Prot |
|
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