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ENZYME

ENZYME entry: EC 1.14.14.88

Accepted Name
isoflavone 3'-hydroxylase
Alternative Name(s)
CYP81E9
Reaction catalysed
formononetin + O2 + reduced [NADPH--hemoprotein reductase] <=> calycosin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
Comment(s)
  • A cytochrome P450 (heme-thiolate) protein.
  • Also acts on biochanin A and other isoflavones with a 4'-methoxy group.
  • Involved in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain.
  • Formerly EC 1.14.13.52.
Cross-references
BRENDA1.14.14.88
EC2PDB1.14.14.88
ExplorEnz1.14.14.88
PRIAM enzyme-specific profiles1.14.14.88
KEGG Ligand Database for Enzyme Nomenclature1.14.14.88
IUBMB Enzyme Nomenclature1.14.14.88
IntEnz1.14.14.88
MEDLINEFind literature relating to 1.14.14.88
MetaCyc1.14.14.88
Rhea expert-curated reactions1.14.14.88
UniProtKB/Swiss-Prot
Q6WNQ9, C81E9_MEDTR

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