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ENZYME entry: EC 1.14.14.91

Accepted Name
Trans-cinnamate 4-monooxygenase.
Alternative Name(s)
CA4H.
Cinnamate 4-hydroxylase.
Cinnamate 4-monooxygenase.
Cinnamic acid 4-hydroxylase.
Cinnamic acid 4-monooxygenase.
CYP73A1.
Reaction catalysed
Trans-cinnamate + [reduced NADPH--hemoprotein reductase] + O(2) <=> 4-hydroxycinnamate + [oxidized NADPH--hemoprotein reductase] + H(2)O
Cofactor(s)
Heme-thiolate.
Comment(s)
  • A cytochrome P450 (heme-thiolate) protein found in plants.
  • The enzyme is involved in flavonoid biosynthesis.
  • Formerly EC 1.14.13.11.
Cross-references
PROSITEPDOC00081
BRENDA1.14.14.91
EC2PDB1.14.14.91
ExplorEnz1.14.14.91
PRIAM enzyme-specific profiles1.14.14.91
KEGG Ligand Database for Enzyme Nomenclature1.14.14.91
IUBMB Enzyme Nomenclature1.14.14.91
IntEnz1.14.14.91
MEDLINEFind literature relating to 1.14.14.91
MetaCyc1.14.14.91
UniProtKB/Swiss-Prot
P92994, TCMO_ARATH;  P48522, TCMO_CATRO;  O81928, TCMO_CICAR;  
Q96423, TCMO_GLYEC;  Q04468, TCMO_HELTU;  P37114, TCMO_MEDSA;  
Q43067, TCMO_PEA;  Q43033, TCMO_PETCR;  Q43054, TCMO_POPKI;  
O24312, TCMO_POPTM;  Q9AR74, TCMO_RUTGR;  Q42797, TCMO_SOYBN;  
P37115, TCMO_VIGRR;  Q43240, TCMO_ZINVI;  

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