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ENZYME entry: EC 1.14.14.95

Accepted Name
Germacrene A hydroxylase.
Reaction catalysed
(+)-germacrene A + 3 [reduced NADPH--hemoprotein reductase] + 3 O(2) <=> germacra-1(10),4,11(13)-trien-12-oate + 3 [oxidized NADPH--hemoprotein reductase] + 4 H(2)O
Cofactor(s)
Heme-thiolate.
Comment(s)
  • A cytochrome P450 (heme-thiolate) protein.
  • This plant enzyme catalyzes three steps in a pathway that leads to the biosynthesis of many sesquiterpenoid lactones.
  • Formerly EC 1.14.13.123.
Cross-references
BRENDA1.14.14.95
EC2PDB1.14.14.95
ExplorEnz1.14.14.95
PRIAM enzyme-specific profiles1.14.14.95
KEGG Ligand Database for Enzyme Nomenclature1.14.14.95
IUBMB Enzyme Nomenclature1.14.14.95
IntEnz1.14.14.95
MEDLINEFind literature relating to 1.14.14.95
MetaCyc1.14.14.95
UniProtKB/Swiss-Prot
D5JBX1, GAO_BARSP;  D5JBW8, GAO_CICIN;  D5JBX0, GAO_HELAN;  
D5J9U8, GAO_LACSA;  D5JBW9, GAO_SAUCO;  X2JI34, GAO_TANPA;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.14.-
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