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ENZYME entry: EC 1.14.15.14

Accepted Name
Methyl-branched lipid omega-hydroxylase.
Alternative Name(s)
CYP124.
Reaction catalysed
A methyl-branched lipid + O(2) + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H(+) <=> an omega-hydroxy-methyl-branched lipid + H(2)O + 2 oxidized ferredoxin [iron-sulfur] cluster
Comment(s)
The enzyme, found in pathogenic and nonpathogenic mycobacteria species, actinomycetes, and some proteobacteria, hydroxylates the omega-carbon of a number of methyl-branched lipids, including (2E,6E)-farnesol, phytanate, geranylgeraniol, 15-methylpalmitate and (2E,6E)-farnesyl diphosphate.
Cross-references
BRENDA1.14.15.14
EC2PDB1.14.15.14
ExplorEnz1.14.15.14
PRIAM enzyme-specific profiles1.14.15.14
KEGG Ligand Database for Enzyme Nomenclature1.14.15.14
IUBMB Enzyme Nomenclature1.14.15.14
IntEnz1.14.15.14
MEDLINEFind literature relating to 1.14.15.14
MetaCyc1.14.15.14
UniProtKB/Swiss-Prot
P0A517, CP124_MYCBO;  P9WPP2, CP124_MYCTO;  P9WPP3, CP124_MYCTU;  

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