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ENZYME

ENZYME entry: EC 1.14.15.18

Accepted Name
calcidiol 1-monooxygenase
Alternative Name(s)
25-hydroxycholecalciferol 1-hydroxylase
25-hydroxycholecalciferol 1-monooxygenase
25-hydroxyvitamin D-1 alpha hydroxylase
25-hydroxyvitamin D3 1alpha-hydroxylase
25-OHD-1 alpha-hydroxylase
Reaction catalysed
  • calcidiol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = calcitriol + H2O + 2 oxidized [adrenodoxin]
  • 2 H(+) + O2 + 2 reduced [adrenodoxin] + secalciferol = calcitetrol + H2O + 2 oxidized [adrenodoxin]
Comment(s)
Formerly EC 1.14.13.13.
Cross-references
BRENDA1.14.15.18
EC2PDB1.14.15.18
ExplorEnz1.14.15.18
PRIAM enzyme-specific profiles1.14.15.18
KEGG Ligand Database for Enzyme Nomenclature1.14.15.18
IUBMB Enzyme Nomenclature1.14.15.18
IntEnz1.14.15.18
MEDLINEFind literature relating to 1.14.15.18
MetaCyc1.14.15.18
Rhea expert-curated reactions1.14.15.18
UniProtKB/Swiss-Prot
O15528, CP27B_HUMANO35084, CP27B_MOUSEO35132, CP27B_RAT

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