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ENZYME entry: EC 1.14.15.19
Accepted Name |
C-19 steroid 1alpha-hydroxylase.
|
Alternative Name(s) |
CYP260A1. |
Reaction catalysed |
2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + testosterone <=> 1alpha-hydroxytestosterone + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] |
Comment(s) |
- The enzyme, characterized from the bacterium Sorangium cellulosum,
is a class I cytochrome P450, and uses ferredoxin as its electron
donor.
- It was shown to act on several C-19 steroid substrates, including
testosterone, androstenedione, testosterone-acetate and
11-oxoandrostenedione.
|
Cross-references |
BRENDA | 1.14.15.19 |
EC2PDB | 1.14.15.19 |
ExplorEnz | 1.14.15.19 |
PRIAM enzyme-specific profiles | 1.14.15.19 |
KEGG Ligand Database for Enzyme Nomenclature | 1.14.15.19 |
IUBMB Enzyme Nomenclature | 1.14.15.19 |
IntEnz | 1.14.15.19 |
MEDLINE | Find literature relating to 1.14.15.19 |
MetaCyc | 1.14.15.19 |
Rhea expert-curated reactions | 1.14.15.19 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.14.15.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-