ID   1.14.15.30
DE   3-ketosteroid 9alpha-monooxygenase.
AN   3-ketosteroid 9alpha-hydroxylase.
CA   androsta-1,4-diene-3,17-dione + 2 H(+) + O2 + 2 reduced [2Fe-2S]-
CA   [ferredoxin] = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + H2O +
CA   2 oxidized [2Fe-2S]-[ferredoxin].
CC   -!- The enzyme is involved in the cholesterol degradation pathway of
CC       several bacterial pathogens, such as Mycobacterium tuberculosis.
CC   -!- It forms a two-component system with a ferredoxin reductase (KshB).
CC   -!- The enzyme contains a Rieske-type iron-sulfur center and non-heme
CC       iron.
CC   -!- The product of the enzyme is unstable, and spontaneously converts to
CC       3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione.
CC   -!- Formerly EC 1.14.13.142.
DR   F1CMX0, KSHA1_RHORH;  F1CMX8, KSHA3_RHORH;  B6V6V5, KSHA4_RHORH;
DR   F1CMY8, KSHA5_RHORH;  A0R4R3, KSHA_MYCS2 ;  P71875, KSHA_MYCTU ;
DR   A0R525, KSHB_MYCS2 ;  P9WJ92, KSHB_MYCTO ;  P9WJ93, KSHB_MYCTU ;
DR   B6V6V6, KSHB_RHORH ;
//