ID   1.14.15.37
DE   Luteothin monooxygenase.
CA   Luteothin + 2 O(2) + 4 reduced ferredoxin [iron-sulfur] cluster + 4 H(+)
CA   = aureothin + 3 H(2)O + 4 oxidized ferredoxin [iron-sulfur] cluster.
CC   -!- The enzyme, characterized from the bacterium Streptomyces thioluteus,
CC       is a bifunctional cytochrome P450 (heme-thiolate) protein that
CC       catalyzes both the hydroxylation of its substrate and formation of a
CC       furan ring, the final step in the biosynthesis of the antibiotic
CC       aureothin.
CC   -!- In the bacteria Streptomyces orinoci and Streptomyces spectabilis an
CC       orthologous enzyme catalyzes a similar reaction that forms
CC       spectinabilin.
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