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ENZYME entry: EC 1.14.15.4
Accepted Name |
steroid 11beta-monooxygenase.
|
Alternative Name(s) |
cytochrome p450 XIB1. |
steroid 11beta/18-hydroxylase. |
steroid 11beta-hydroxylase. |
Reaction catalysed |
a steroid + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> an 11beta-hydroxysteroid + H2O + 2 oxidized [adrenodoxin] |
Comment(s) |
- Also hydroxylates steroids at the 18-position, and converts
18-hydroxycorticosterone into aldosterone.
- Formerly EC 1.14.1.6 and EC 1.99.1.7.
|
Cross-references |
BRENDA | 1.14.15.4 |
EC2PDB | 1.14.15.4 |
ExplorEnz | 1.14.15.4 |
PRIAM enzyme-specific profiles | 1.14.15.4 |
KEGG Ligand Database for Enzyme Nomenclature | 1.14.15.4 |
IUBMB Enzyme Nomenclature | 1.14.15.4 |
IntEnz | 1.14.15.4 |
MEDLINE | Find literature relating to 1.14.15.4 |
MetaCyc | 1.14.15.4 |
Rhea expert-curated reactions | 1.14.15.4 |
UniProtKB/Swiss-Prot |
P15150, C11B1_BOVIN; | Q64408, C11B1_CAVPO; | P15538, C11B1_HUMAN; |
P97720, C11B1_MESAU; | Q29527, C11B1_PAPHU; | Q29552, C11B1_PIG; |
P15393, C11B1_RAT; | P51663, C11B1_SHEEP; | P19099, C11B2_HUMAN; |
Q64658, C11B2_MESAU; | P15539, C11B2_MOUSE; | P30099, C11B2_RAT; |
P30100, C11B3_RAT; | Q92104, CP11B_LITCT; |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.14.15.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
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