ID   1.14.15.45
DE   4-hydroxy-3-polyprenylbenzoate 5-hydroxylase.
CA   a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + 2 reduced [2Fe-2S]-
CA   [ferredoxin] + O2 + 2 H(+) = a 3,4-dihydroxy-5-(all-trans-
CA   polyprenyl)benzoate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O.
CC   -!- The enzyme, found in eukaryotes, is involved in the biosynthesis of
CC       ubiquinone.
CC   -!- The vertebrate enzyme catalyzes two hydroxylations in the pathway at
CC       the positions meta to the prenyl side chain (the other hydroxylation
CC       is classified as EC 1.14.15.46).
CC   -!- The number of isoprenoid subunits in the side chain varies in
CC       different species.
CC   -!- The enzyme does not have any specificity concerning the length of the
CC       polyprenyl tail, and accepts tails of various lengths with similar
CC       efficiency.
DR   Q2KIL4, COQ6_BOVIN ;  O01884, COQ6_CAEEL ;  F1RAX8, COQ6_DANRE ;
DR   Q54EN1, COQ6_DICDI ;  Q9VMQ5, COQ6_DROME ;  Q9Y2Z9, COQ6_HUMAN ;
DR   Q8R1S0, COQ6_MOUSE ;  Q68FU7, COQ6_RAT   ;  Q9Y7Z9, COQ6_SCHPO ;
DR   Q6DF46, COQ6_XENTR ;  P53318, COQ6_YEAST ;
//