ENZYME entry: EC 1.14.15.8
Accepted Name |
Steroid 15-beta-monooxygenase.
|
Alternative Name(s) |
CYP106A2. |
Steroid 15-beta-hydroxylase. |
Reaction catalysed |
Progesterone + 2 reduced [2Fe-2S] ferredoxin + O(2) <=> 15-beta-hydroxyprogesterone + 2 oxidized [2Fe-2S] ferredoxin + H(2)O |
Comment(s) |
- The enzyme from Bacillus megaterium hydroxylates a variety of 3-oxo-
Delta-4-steroids in position 15-beta.
- Ring A-reduced, aromatic, and 3-beta-hydroxy-Delta-4-steroids do not
serve as substrates.
|
Cross-references |
PROSITE | PDOC00081 |
BRENDA | 1.14.15.8 |
EC2PDB | 1.14.15.8 |
ExplorEnz | 1.14.15.8 |
PRIAM enzyme-specific profiles | 1.14.15.8 |
KEGG Ligand Database for Enzyme Nomenclature | 1.14.15.8 |
IUBMB Enzyme Nomenclature | 1.14.15.8 |
IntEnz | 1.14.15.8 |
MEDLINE | Find literature relating to 1.14.15.8 |
MetaCyc | 1.14.15.8 |
UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.14.15.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-