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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.14.17.4

Accepted Name
Aminocyclopropanecarboxylate oxidase.
Alternative Name(s)
1-aminocyclopropane-1-carboxylate oxidase.
ACC oxidase.
Ethylene-forming enzyme.
Reaction catalysed
1-aminocyclopropane-1-carboxylate + ascorbate + O(2) <=> ethylene + cyanide + dehydroascorbate + CO(2) + 2 H(2)O
Cofactor(s)
Fe cation.
Comment(s)
  • Requires CO(2) for activity.
  • In the enzyme from plants, the ethylene has signaling functions such as stimulation of fruit-ripening.
Cross-references
PROSITEPDOC51471
BRENDA1.14.17.4
EC2PDB1.14.17.4
ExplorEnz1.14.17.4
PRIAM enzyme-specific profiles1.14.17.4
KEGG Ligand Database for Enzyme Nomenclature1.14.17.4
IUBMB Enzyme Nomenclature1.14.17.4
IntEnz1.14.17.4
MEDLINEFind literature relating to 1.14.17.4
MetaCyc1.14.17.4
UniProtKB/Swiss-Prot
Q9ZUN4, ACCO1_ARATH;  Q09052, ACCO1_BRAJU;  Q04644, ACCO1_CUCME;  
Q76NT9, ACCO1_DICDI;  A6BM06, ACCO1_DICMU;  P31238, ACCO1_DORSP;  
Q00985, ACCO1_MALDO;  A2Z1W9, ACCO1_ORYSI;  Q0J1C1, ACCO1_ORYSJ;  
Q08506, ACCO1_PETHY;  P05116, ACCO1_SOLLC;  Q41931, ACCO2_ARATH;  
Q39705, ACCO2_DORSP;  O48882, ACCO2_MALDO;  P07920, ACCO2_SOLLC;  
O65378, ACCO3_ARATH;  P54847, ACCO3_CUCME;  Q08507, ACCO3_PETHY;  
Q06588, ACCO4_ARATH;  Q08508, ACCO4_PETHY;  P24157, ACCO4_SOLLC;  
Q0WPW4, ACCO5_ARATH;  P31237, ACCO_ACTDE;  Q9ZQZ1, ACCO_DENCR;  
P31528, ACCO_DIACA;  Q8S932, ACCO_DIOKA;  Q9FR99, ACCO_MUSAC;  
P31239, ACCO_PEA;  P19464, ACCO_PERAE;  Q9MB94, ACCO_PRUMU;  
Q43792, ACCO_TOBAC;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.17.-
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