Home  |  Contact

ENZYME entry: EC 1.14.18.4

Accepted Name
phosphatidylcholine 12-monooxygenase.
Alternative Name(s)
oleate Delta(12)-hydroxylase.
ricinoleic acid synthase.
Reaction catalysed
1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 1-acyl-2-[(R)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + H2O
Comment(s)
  • The enzyme, characterized from the plant Ricinus communis (castor bean), is involved in production of the 12-hydroxylated fatty acid ricinoleate.
  • The enzyme requires a cytochrome b5 as the electron donor.
  • Formerly EC 1.14.13.26.
Cross-references
BRENDA1.14.18.4
EC2PDB1.14.18.4
ExplorEnz1.14.18.4
PRIAM enzyme-specific profiles1.14.18.4
KEGG Ligand Database for Enzyme Nomenclature1.14.18.4
IUBMB Enzyme Nomenclature1.14.18.4
IntEnz1.14.18.4
MEDLINEFind literature relating to 1.14.18.4
MetaCyc1.14.18.4
Rhea expert-curated reactions1.14.18.4
UniProtKB/Swiss-Prot
Q41131, FAH12_RICCO

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.18.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-