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ENZYME entry: EC 1.14.18.4
| Accepted Name |
|---|
| phosphatidylcholine 12-monooxygenase.
|
| Alternative Name(s) |
|---|
| oleate Delta(12)-hydroxylase. |
| ricinoleic acid synthase. |
| Reaction catalysed |
|---|
| 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 1-acyl-2-[(R)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + H2O |
| Comment(s) |
|---|
- The enzyme, characterized from the plant Ricinus communis (castor
bean), is involved in production of the 12-hydroxylated fatty acid
ricinoleate.
- The enzyme requires a cytochrome b5 as the electron donor.
- Formerly EC 1.14.13.26.
|
| Cross-references |
|---|
| BRENDA | 1.14.18.4 |
| EC2PDB | 1.14.18.4 |
| ExplorEnz | 1.14.18.4 |
| PRIAM enzyme-specific profiles | 1.14.18.4 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.18.4 |
| IUBMB Enzyme Nomenclature | 1.14.18.4 |
| IntEnz | 1.14.18.4 |
| MEDLINE | Find literature relating to 1.14.18.4 |
| MetaCyc | 1.14.18.4 |
| Rhea expert-curated reactions | 1.14.18.4 |
| UniProtKB/Swiss-Prot |
|
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