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ENZYME entry: EC 1.14.18.4

Accepted Name
Phosphatidylcholine 12-monooxygenase.
Alternative Name(s)
Oleate Delta(12)-hydroxylase.
Ricinoleic acid synthase.
Reaction catalysed
A 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + 2 ferrocytochrome b5 + O(2) + 2 H(+) <=> a 1-acyl-2-((12R)-12-hydroxyoleoyl)-sn-glycero-3-phosphocholine + 2 ferricytochrome b5 + H(2)O
Comment(s)
  • The enzyme, characterized from the plant Ricinus communis (castor bean), is involved in production of the 12-hydroxylated fatty acid ricinoleate.
  • The enzyme requires a cytochrome b5 as the electron donor.
  • Formerly EC 1.14.13.26.
Cross-references
BRENDA1.14.18.4
EC2PDB1.14.18.4
ExplorEnz1.14.18.4
PRIAM enzyme-specific profiles1.14.18.4
KEGG Ligand Database for Enzyme Nomenclature1.14.18.4
IUBMB Enzyme Nomenclature1.14.18.4
IntEnz1.14.18.4
MEDLINEFind literature relating to 1.14.18.4
MetaCyc1.14.18.4
UniProtKB/Swiss-Prot
Q41131, FAH12_RICCO

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