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ENZYME

ENZYME entry: EC 1.14.19.10

Accepted Name
icosanoyl-CoA 5-desaturase
Alternative Name(s)
acyl-CoA Delta(5)-desaturase
Reaction catalysed
eicosanoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (5Z)-eicosenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
Comment(s)
  • The enzyme, characterized from the plant Limnanthes douglasii (meadowfoam), is involved in the biosynthesis of (5Z)-icos-5-enoate, an unusual monounsaturated fatty acid that makes up to 60% of the total fatty acids in Limnanthes sp. seed oil.
  • The enzyme only acts on saturated fatty acids.
Cross-references
BRENDA1.14.19.10
EC2PDB1.14.19.10
ExplorEnz1.14.19.10
PRIAM enzyme-specific profiles1.14.19.10
KEGG Ligand Database for Enzyme Nomenclature1.14.19.10
IUBMB Enzyme Nomenclature1.14.19.10
IntEnz1.14.19.10
MEDLINEFind literature relating to 1.14.19.10
MetaCyc1.14.19.10
Rhea expert-curated reactions1.14.19.10
UniProtKB/Swiss-Prot
Q9FV68, ICO5D_LIMDO

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