ENZYME entry: EC 1.14.19.13

Accepted Name
Acyl-CoA 15-desaturase.
Reaction catalysed
(9Z,12Z)-hexadeca-9,12-dienoyl-CoA + reduced acceptor + O(2) <=> (9Z,12Z,15Z)-hexadeca-9,12,15-trienoyl-CoA + acceptor + 2 H(2)O
Comment(s)
  • The enzyme, characterized from the the plant Sorghum bicolor, is involved in the biosynthesis of sorgoleone, an allelopathic compound produced in root hair cells.
  • The enzyme inserts a cis double bond at carbon 15.
  • When acting on its natural substrate, (9Z,12Z)-hexadeca-9,12-dienoyl- CoA, it produces a product with a terminal double bond.
Cross-references
BRENDA1.14.19.13
EC2PDB1.14.19.13
ExplorEnz1.14.19.13
PRIAM enzyme-specific profiles1.14.19.13
KEGG Ligand Database for Enzyme Nomenclature1.14.19.13
IUBMB Enzyme Nomenclature1.14.19.13
IntEnz1.14.19.13
MEDLINEFind literature relating to 1.14.19.13
MetaCyc1.14.19.13
UniProtKB/Swiss-Prot
Q594P3, DES3_SORBI

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