ID 1.14.19.20 DE Delta(7)-sterol 5(6)-desaturase. AN 5-DES. AN Delta(7)-sterol 5-desaturase. AN Delta(7)-sterol-C5(6)-desaturase. AN Delta(7)-sterol Delta(5)-dehydrogenase. AN lathosterol 5-desaturase. AN lathosterol oxidase. CA a Delta(7)-sterol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = CA a Delta(5),Delta(7)-sterol + 2 Fe(III)-[cytochrome b5] + 2 H2O. CC -!- This enzyme, found in eukaryotic organisms, catalyzes the CC introduction of a double bond between the C5 and C6 carbons of the B CC ring of Delta(7)-sterols, to yield the corresponding Delta(5,7)- CC sterols. CC -!- The enzymes from yeast, plants and vertebrates act on avenasterol, CC episterol, and lathosterol, respectively. CC -!- The enzyme is located at the endoplasmic reticulum and is membrane CC bound. CC -!- Formerly EC 1.3.3.2 and EC 1.14.21.6. DR I1RFM2, ERG3A_GIBZE; O94457, ERG3A_SCHPO; A0A0E0SNE8, ERG3B_GIBZE; DR O13666, ERG3B_SCHPO; Q59VG6, ERG3_CANAL ; O93875, ERG3_CANAX ; DR Q8NJ57, ERG3_CANDC ; P50860, ERG3_CANGA ; Q754B9, ERG3_EREGS ; DR Q8J207, ERG3_LEPMC ; Q7SBB6, ERG3_NEUCR ; P32353, ERG3_YEAST ; DR Q39208, SC5D1_ARATH; Q9M883, SC5D2_ARATH; O75845, SC5D_HUMAN ; DR O88822, SC5D_MOUSE ; Q9EQS5, SC5D_RAT ; Q9ZT29, SC5D_TOBAC ; //