ID   1.14.19.20
DE   Delta(7)-sterol 5(6)-desaturase.
AN   5-DES.
AN   Delta(7)-sterol 5-desaturase.
AN   Delta(7)-sterol-C5(6)-desaturase.
AN   Delta(7)-sterol Delta(5)-dehydrogenase.
AN   lathosterol 5-desaturase.
AN   lathosterol oxidase.
CA   a Delta(7)-sterol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 =
CA   a Delta(5),Delta(7)-sterol + 2 Fe(III)-[cytochrome b5] + 2 H2O.
CC   -!- This enzyme, found in eukaryotic organisms, catalyzes the
CC       introduction of a double bond between the C5 and C6 carbons of the B
CC       ring of Delta(7)-sterols, to yield the corresponding Delta(5,7)-
CC       sterols.
CC   -!- The enzymes from yeast, plants and vertebrates act on avenasterol,
CC       episterol, and lathosterol, respectively.
CC   -!- The enzyme is located at the endoplasmic reticulum and is membrane
CC       bound.
CC   -!- Formerly EC 1.3.3.2 and EC 1.14.21.6.
DR   I1RFM2, ERG3A_GIBZE;  O94457, ERG3A_SCHPO;  A0A0E0SNE8, ERG3B_GIBZE;
DR   O13666, ERG3B_SCHPO;  Q59VG6, ERG3_CANAL ;  O93875, ERG3_CANAX ;
DR   Q8NJ57, ERG3_CANDC ;  P50860, ERG3_CANGA ;  Q754B9, ERG3_EREGS ;
DR   Q8J207, ERG3_LEPMC ;  Q7SBB6, ERG3_NEUCR ;  P32353, ERG3_YEAST ;
DR   Q39208, SC5D1_ARATH;  Q9M883, SC5D2_ARATH;  O75845, SC5D_HUMAN ;
DR   O88822, SC5D_MOUSE ;  Q9EQS5, SC5D_RAT   ;  Q9ZT29, SC5D_TOBAC ;
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