A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.14.19.25
| Accepted Name |
|---|
| Acyl-lipid omega-3 desaturase (cytochrome b5).
|
| Reaction catalysed |
|---|
| A linoleoyl-[glycerolipid] + 2 ferrocytochrome b5 + O(2) + 2 H(+) <=> an alpha-linolenoyl-[glycerolipid] + ferricytochrome b5 + 2 H(2)O |
| Comment(s) |
|---|
- This microsomal enzyme introduces a cis double bond three carbons
away from the methyl end of a fatty acid incorporated into a
glycerolipid.
- The distance from the carboxylic acid end of the molecule does not
have an effect.
- The plant enzyme acts on carbon 15 of linoleoyl groups incorporated
into both the sn-1 and sn-2 positions of the glycerol backbone of
phosphatidylcholine and other phospholipids, converting them into
alpha-linolenoyl groups.
- The enzyme from the fungus Mortierella alpina acts on gamma-
linolenoyl and arachidonoyl groups, converting them into stearidonoyl
and icosapentaenoyl groups, respectively.
- Cf. EC 1.14.19.35.
|
| Cross-references |
|---|
| BRENDA | 1.14.19.25 |
| EC2PDB | 1.14.19.25 |
| ExplorEnz | 1.14.19.25 |
| PRIAM enzyme-specific profiles | 1.14.19.25 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.19.25 |
| IUBMB Enzyme Nomenclature | 1.14.19.25 |
| IntEnz | 1.14.19.25 |
| MEDLINE | Find literature relating to 1.14.19.25 |
| MetaCyc | 1.14.19.25 |
| UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.14.19.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-