A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.14.19.50
| Accepted Name |
|---|
| Noroxomaritidine synthase.
|
| Alternative Name(s) |
|---|
| CYP96T1. |
| Reaction catalysed |
|---|
- 4'-O-methylnorbelladine + [reduced NADPH--hemoprotein reductase] + O(2) <=> (10bS,4aR)-noroxomaritidine + [oxidized NADPH--hemoprotein reductase] + 2 H(2)O
- 4'-O-methylnorbelladine + [reduced NADPH--hemoprotein reductase] + O(2) <=> (10bR,4aS)-noroxomaritidine + [oxidized NADPH--hemoprotein reductase] + 2 H(2)O
|
| Cofactor(s) |
|---|
| Heme-thiolate.
|
| Comment(s) |
|---|
- The enzyme, characterized from Narcissus aff pseudonarcissus
(daffodil), forms the two enantiomers of the Amaryllidacea alkaloid
noroxomaritidine by catalyzing intramolecular oxidative para-para'
phenol coupling.
- The oxidation involves molecular oxygen without its incorporation
into the product.
|
| Cross-references |
|---|
| BRENDA | 1.14.19.50 |
| EC2PDB | 1.14.19.50 |
| ExplorEnz | 1.14.19.50 |
| PRIAM enzyme-specific profiles | 1.14.19.50 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.19.50 |
| IUBMB Enzyme Nomenclature | 1.14.19.50 |
| IntEnz | 1.14.19.50 |
| MEDLINE | Find literature relating to 1.14.19.50 |
| MetaCyc | 1.14.19.50 |
| UniProtKB/Swiss-Prot |
|
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UniProtKB/Swiss-Prot entries corresponding to 1.14.19.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
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