Expasy logo

ENZYME

ENZYME entry: EC 1.14.19.52

Accepted Name
camalexin synthase
Alternative Name(s)
bifunctional dihydrocamalexate synthase/camalexin synthase
CYP71B15
Reaction catalysed
2-(L-cystein-S-yl)-2-(1H-indol-3-yl)-acetonitrile + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = camalexin + CO2 + 2 H(+) + 4 H2O + hydrogen cyanide + 2 oxidized [NADPH--hemoprotein reductase]
Comment(s)
  • This P450 enzyme, which has been characterized from the plant Arabidopsis thaliana, catalyzes the last two steps in the biosynthesis of camalexin, the main phytoalexin in that plant.
  • The enzyme catalyzes two successive oxidation events.
  • During the first of oxidation the enzyme introduces a C-N double bond, liberating hydrogen cyanide, and during the second oxidation it catalyzes a decarboxylation.
  • Formerly EC 1.3.1.n2.
Cross-references
BRENDA1.14.19.52
EC2PDB1.14.19.52
ExplorEnz1.14.19.52
PRIAM enzyme-specific profiles1.14.19.52
KEGG Ligand Database for Enzyme Nomenclature1.14.19.52
IUBMB Enzyme Nomenclature1.14.19.52
IntEnz1.14.19.52
MEDLINEFind literature relating to 1.14.19.52
MetaCyc1.14.19.52
Rhea expert-curated reactions1.14.19.52
UniProtKB/Swiss-Prot
Q9LW27, C71BF_ARATH

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.19.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-