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ENZYME entry: EC 1.14.19.53

Accepted Name
All-trans-retinol 3,4-desaturase.
Alternative Name(s)
CYP27C1.
Reaction catalysed
All-trans-retinol + 2 reduced adrenodoxin + 2 H(+) + O(2) <=> all-trans-3,4-didehydroretinol + 2 oxidized adrenodoxin + 2 H(2)O
Comment(s)
  • A cytochrome P450 (heme thiolate) enzyme found in vertebrates.
  • The enzyme is also active with retinal and retinoic acid.
Cross-references
BRENDA1.14.19.53
EC2PDB1.14.19.53
ExplorEnz1.14.19.53
PRIAM enzyme-specific profiles1.14.19.53
KEGG Ligand Database for Enzyme Nomenclature1.14.19.53
IUBMB Enzyme Nomenclature1.14.19.53
IntEnz1.14.19.53
MEDLINEFind literature relating to 1.14.19.53
MetaCyc1.14.19.53
Rhea expert-curated reactions1.14.19.53
UniProtKB/Swiss-Prot
A8WGA0, C27C1_DANRE;  Q4G0S4, C27C1_HUMAN;  P0DOX0, C27C1_LITCT;  

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