ID   1.14.19.55
DE   4-hydroxybenzoate brominase (decarboxylating).
CA   (1) 4-hydroxybenzoate + 2 bromide + 5 H(+) + 2 NADPH + 2 O2 = 2,4-
CA   dibromophenol + CO2 + 4 H2O + 2 NADP(+).
CA   (2) 3,4-dihydroxybenzoate + 2 bromide + 5 H(+) + 2 NADPH + 2 O2 = 3,5-
CA   dibromobenzene-1,2-diol + CO2 + 4 H2O + 2 NADP(+).
CC   -!- The enzyme, described from epiphytic marine bacteria of the genera
CC       Pseudoalteromonas and Marinomonas, is an unusual single-component
CC       FAD-dependent halogenase that contains a distinct NAD(P)H binding
CC       domain and does not require an additional flavin reductase for
CC       activity.
CC   -!- The enzyme catalyzes a bromination of its substrate, followed by a
CC       second bromination concurrent with decarboxylation.
DR   F2K079, BMP5_MARM1 ;  V4HM83, BMP5_PSEL2 ;
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