ID 1.14.19.60 DE 7-chloro-L-tryptophan 6-halogenase. CA 7-chloro-L-tryptophan + chloride + FADH2 + O2 = 6,7-dichloro-L-tryptophan CA + FAD + 2 H2O. CC -!- An FAD-dependent halogenase. CC -!- The enzyme, characterized from the bacterium Kutzneria sp. 744, works CC in tandem with EC 1.14.19.9 to generate 6,7-dichloro-L-tryptophan, CC which is incorporated as a pyrroloindoline in the kutznerides family CC of natural products. CC -!- It has a 120-fold preference for 7-chloro-L-tryptophan over CC L-tryptophan as substrate. DR A8CF74, 7CT6H_KUTS7; //