ID   1.14.19.65
DE   (S)-cheilanthifoline synthase.
AN   (S)-scoulerine oxidase (methylenedioxy-bridge-forming).
AN   CYP719A14.
CA   (S)-scoulerine + O2 + reduced [NADPH--hemoprotein reductase] = (S)-
CA   cheilanthifoline + H(+) + 2 H2O + oxidized [NADPH--hemoprotein
CA   reductase].
CC   -!- A cytochrome P450 (heme-thiolate) protein catalyzing an oxidative
CC       reaction that does not incorporate oxygen into the product.
CC   -!- Forms the methylenedioxy bridge of the protoberberine alkaloid
CC       cheilanthifoline by the oxidative ring closure of adjacent phenolic
CC       and methoxy groups of scoulerine. cf. EC 1.14.19.73 which catalyzes a
CC       similar reaction at the other side of the (S)-scoulerine molecule,
CC       forming (S)-nandinine.
CC   -!- Formerly EC 1.1.3.33 and EC 1.14.21.2.
DR   B5UAQ8, C7195_ESCCA;  B1NF20, C719E_ARGME;
//