ID   1.14.19.72
DE   (-)-pluviatolide synthase.
AN   CYP719A23.
CA   (-)-matairesinol + O2 + reduced [NADPH--hemoprotein reductase] = (-)-
CA   pluviatolide + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase].
CC   -!- A cytochrome P450 (heme-thiolate) protein.
CC   -!- The enzyme from the plants Sinopodophyllum hexandrum and Podophyllum
CC       peltatum catalyzes the formation of a methylenedioxy-bridge.
CC   -!- It is involved in the biosynthesis of podophyllotoxin, a non-alkaloid
CC       toxin lignan whose derivatives are important anticancer drugs.
CC   -!- Formerly EC 1.14.21.11.
DR   L7T720, C719A_PODPE;  L7T8H2, C719A_SINHE;
//