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ENZYME

ENZYME entry: EC 1.14.19.79

PURL: https://purl.expasy.org/enzyme/EC/1.14.19.79
Accepted Name
3beta,22alpha-dihydroxysteroid 3-dehydrogenase
Alternative Name(s)
CYP90A1
Reaction catalysed
  • (22S)-22-hydroxycampesterol + reduced [NADPH--hemoprotein reductase] + O2 = (22S)-22-hydroxycampest-4-en-3-one + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)
  • 6-deoxoteasterone + reduced [NADPH--hemoprotein reductase] + O2 = 3-dehydro-6-deoxoteasterone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)
Comment(s)
This cytochrome P450 (heme-thiolate) enzyme, characterized from the plant Arabidopsis thaliana, catalyzes C-3 dehydrogenation of all 3beta-hydroxy brassinosteroid synthesis intermediates with 22-hydroxylated or 2(2),2(3)-dihydroxylated side chains.
Cross-references
BRENDA1.14.19.79
EC2PDB1.14.19.79
ExplorEnz1.14.19.79
KEGG Ligand Database for Enzyme Nomenclature1.14.19.79
IUBMB Enzyme Nomenclature1.14.19.79
MEDLINEFind literature relating to 1.14.19.79
MetaCyc1.14.19.79
Rhea expert-curated reactions1.14.19.79
UniProtKB/Swiss-Prot
Q42569, C90A1_ARATHI1IUJ6, C90A1_BRADI

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