ID   1.14.20.11
DE   3-[(Z)-2-isocyanoethenyl]-1H-indole synthase.
CA   (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) +
CA   O2 = 3-[(Z)-2-isocyanoethenyl]-1H-indole + 2 CO2 + H2O + succinate.
CC   -!- The enzyme, characterized from the cyanobacterium Fischerella ambigua
CC       UTEX 1903, participates in the biosynthesis of hapalindole-type
CC       alkaloids.
CC   -!- The enzyme catalyzes an Fe(2+), 2-oxoglutarate-dependent
CC       monooxygenation at C-3, which is followed by decarboxylation and
CC       dehydration, resulting in the generation of a cis C-C double bond.
CC       cf. EC 1.14.20.12.
DR   V5TD18, AMBI3_FISAU;
//